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Selected Publications

LaTourette PC 2nd, Awasthi S, Desmond A, Pardi N, Cohen GH, Weissman D, Friedman HM.: Protection against herpes simplex virus type 2 infection in a neonatal murine model using a trivalent nucleoside-modified mRNA in lipid nanoparticle vaccine. Vaccine 38: 7409-7413, Nov 2020.
Laczkó D, Hogan MJ, Toulmin SA, Hicks P, Lederer K, Gaudette BT, Castaño D, Amanat F, Muramatsu H, Oguin TH 3rd, Ojha A, Zhang L, Mu Z, Parks R, Manzoni TB, Roper B, Strohmeier S, Tombácz I, Arwood L, Nachbagauer R, Karikó K, Greenhouse J, Pessaint L, Porto M, Putman-Taylor T, Strasbaugh A, Campbell TA, Lin PJC, Tam YK, Sempowski GD, Farzan M, Choe H, Saunders KO, Haynes BF, Andersen H, Eisenlohr LC, Weissman D, Krammer F, Bates P, Allman D, Locci M, Pardi N.: A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice. Immunity 53: 724-732, Oct 2020.
Pardi, N., Hogan, M. J., Weissman, D.: Recent advances in mRNA vaccine technology. Curr Opin Immunol. 65:14-20.(doi): 10.1016/j.coi.2020.01.008. Aug 2020.
Egan KP, Hook LM, Naughton A, Pardi N, Awasthi S, Cohen GH, Weissman D, Friedman HM.: An HSV-2 nucleoside-modified mRNA genital herpes vaccine containing glycoproteins gC, gD, and gE protects mice against HSV-1 genital lesions and latent infection. PLoS Pathog 16: e1008795, Jul 2020.
Freyn, A. W., Ramos da Silva, J., Rosado, V. C., Bliss, C. M., Pine, M., Mui, B. L., Tam, Y. K., Madden, T. D., de Souza Ferreira, L. C., Weissman, D., Krammer, F., Coughlan, L., Palese, P., Pardi, N., Nachbagauer, R.: A Multi-Targeting, Nucleoside-Modified mRNA Influenza Virus Vaccine Provides Broad Protection in Mice. Mol Ther 19(20): 30199-4, Jul 2020.
Raj, D. K., Das Mohapatra, A., Jnawali, A., Zuromski, J., Jha, A., Cham-Kpu, G., Sherman, B., Rudlaff, R. M., Nixon, C. E., Hilton, N., Oleinikov, A. V., Chesnokov, O., Merritt, J., Pond-Tor, S., Burns, L., Jolly, G., Ben Mamoun, C., Kabyemela, E., Muehlenbachs, A., Lambert, L., Orr-Gonzalez, S., Gnädig, N. F., Fidock, D. A., Park, S., Dvorin, J. D., Pardi, N., Weissman, D., Mui, B. L., Tam, Y. K., Friedman, J. F., Fried, M., Duffy, P. E., Kurtis, J. D.: Anti-PfGARP activates programmed cell death of parasites and reduces severe malaria. Nature 22(10): 020-2220, Jun 2020.
Johnson JL, Rosenthal RL, Knox JJ, Myles A, Naradikian MS, Madej J, Kostiv M, Rosenfeld AM, Meng W, Christensen SR, Hensley SE, Yewdell J, Canaday DH, Zhu J, McDermott AB, Dori Y, Itkin M, Wherry EJ, Pardi N, Weissman D, Naji A, Prak ETL, Betts MR, Cancro MP.: The Transcription Factor T-bet Resolves Memory B Cell Subsets with Distinct Tissue Distributions and Antibody Specificities in Mice and Humans. Immunity 52: 842-855, May 2020.
Lo, M. K., Spengler, J. R., Welch, S. R., Harmon, J. R., Coleman-McCray, J. D., Scholte, F. E. M., Shrivastava-Ranjan, P., Montgomery, J. M., Nichol, S. T., Weissman, D., Spiropoulou, C. F.: Evaluation of a Single-Dose Nucleoside-Modified Messenger RNA Vaccine Encoding Hendra Virus-Soluble Glycoprotein Against Lethal Nipah virus Challenge in Syrian Hamsters. J Infect Dis. 221(Supplement_4): S493-S498, May 2020.
Nelson CS, Jenks JA, Pardi N, Goodwin M, Roark H, Edwards W, McLellan JS, Pollara J, Weissman D, Permar SR.: Human Cytomegalovirus Glycoprotein B Nucleoside-Modified mRNA Vaccine Elicits Antibody Responses with Greater Durability and Breadth than MF59-Adjuvanted gB Protein Immunization. J Virol 94: e00186-20, Apr 2020.
Ravimohan, S., Auld, S. C., Maenetje, P., Ratsela, N., Mlotshwa, M., Ncube, I., Smith, J. P., Vangu, M. D., Sebe, M., Kossenkov, A., Weissman, D., Wallis, R. S., Churchyard, G., Kornfeld, H., Bisson, G. P.: Lung Injury on Antiretroviral Therapy in Adults With Human Immunodeficiency Virus/Tuberculosis. Clin Infect Dis. 70(9): 1845-1854. doi: 10.1093/cid/ciz560. Apr 2020.

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Selected Publications

LaTourette PC 2nd, Awasthi S, Desmond A, Pardi N, Cohen GH, Weissman D, Friedman HM.: Protection against herpes simplex virus type 2 infection in a neonatal murine model using a trivalent nucleoside-modified mRNA in lipid nanoparticle vaccine. Vaccine 38: 7409-7413, Nov 2020.
Laczkó D, Hogan MJ, Toulmin SA, Hicks P, Lederer K, Gaudette BT, Castaño D, Amanat F, Muramatsu H, Oguin TH 3rd, Ojha A, Zhang L, Mu Z, Parks R, Manzoni TB, Roper B, Strohmeier S, Tombácz I, Arwood L, Nachbagauer R, Karikó K, Greenhouse J, Pessaint L, Porto M, Putman-Taylor T, Strasbaugh A, Campbell TA, Lin PJC, Tam YK, Sempowski GD, Farzan M, Choe H, Saunders KO, Haynes BF, Andersen H, Eisenlohr LC, Weissman D, Krammer F, Bates P, Allman D, Locci M, Pardi N.: A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice. Immunity 53: 724-732, Oct 2020.
Pardi, N., Hogan, M. J., Weissman, D.: Recent advances in mRNA vaccine technology. Curr Opin Immunol. 65:14-20.(doi): 10.1016/j.coi.2020.01.008. Aug 2020.
Egan KP, Hook LM, Naughton A, Pardi N, Awasthi S, Cohen GH, Weissman D, Friedman HM.: An HSV-2 nucleoside-modified mRNA genital herpes vaccine containing glycoproteins gC, gD, and gE protects mice against HSV-1 genital lesions and latent infection. PLoS Pathog 16: e1008795, Jul 2020.
Freyn, A. W., Ramos da Silva, J., Rosado, V. C., Bliss, C. M., Pine, M., Mui, B. L., Tam, Y. K., Madden, T. D., de Souza Ferreira, L. C., Weissman, D., Krammer, F., Coughlan, L., Palese, P., Pardi, N., Nachbagauer, R.: A Multi-Targeting, Nucleoside-Modified mRNA Influenza Virus Vaccine Provides Broad Protection in Mice. Mol Ther 19(20): 30199-4, Jul 2020.
Raj, D. K., Das Mohapatra, A., Jnawali, A., Zuromski, J., Jha, A., Cham-Kpu, G., Sherman, B., Rudlaff, R. M., Nixon, C. E., Hilton, N., Oleinikov, A. V., Chesnokov, O., Merritt, J., Pond-Tor, S., Burns, L., Jolly, G., Ben Mamoun, C., Kabyemela, E., Muehlenbachs, A., Lambert, L., Orr-Gonzalez, S., Gnädig, N. F., Fidock, D. A., Park, S., Dvorin, J. D., Pardi, N., Weissman, D., Mui, B. L., Tam, Y. K., Friedman, J. F., Fried, M., Duffy, P. E., Kurtis, J. D.: Anti-PfGARP activates programmed cell death of parasites and reduces severe malaria. Nature 22(10): 020-2220, Jun 2020.
Johnson JL, Rosenthal RL, Knox JJ, Myles A, Naradikian MS, Madej J, Kostiv M, Rosenfeld AM, Meng W, Christensen SR, Hensley SE, Yewdell J, Canaday DH, Zhu J, McDermott AB, Dori Y, Itkin M, Wherry EJ, Pardi N, Weissman D, Naji A, Prak ETL, Betts MR, Cancro MP.: The Transcription Factor T-bet Resolves Memory B Cell Subsets with Distinct Tissue Distributions and Antibody Specificities in Mice and Humans. Immunity 52: 842-855, May 2020.
Lo, M. K., Spengler, J. R., Welch, S. R., Harmon, J. R., Coleman-McCray, J. D., Scholte, F. E. M., Shrivastava-Ranjan, P., Montgomery, J. M., Nichol, S. T., Weissman, D., Spiropoulou, C. F.: Evaluation of a Single-Dose Nucleoside-Modified Messenger RNA Vaccine Encoding Hendra Virus-Soluble Glycoprotein Against Lethal Nipah virus Challenge in Syrian Hamsters. J Infect Dis. 221(Supplement_4): S493-S498, May 2020.
Nelson CS, Jenks JA, Pardi N, Goodwin M, Roark H, Edwards W, McLellan JS, Pollara J, Weissman D, Permar SR.: Human Cytomegalovirus Glycoprotein B Nucleoside-Modified mRNA Vaccine Elicits Antibody Responses with Greater Durability and Breadth than MF59-Adjuvanted gB Protein Immunization. J Virol 94: e00186-20, Apr 2020.
Ravimohan, S., Auld, S. C., Maenetje, P., Ratsela, N., Mlotshwa, M., Ncube, I., Smith, J. P., Vangu, M. D., Sebe, M., Kossenkov, A., Weissman, D., Wallis, R. S., Churchyard, G., Kornfeld, H., Bisson, G. P.: Lung Injury on Antiretroviral Therapy in Adults With Human Immunodeficiency Virus/Tuberculosis. Clin Infect Dis. 70(9): 1845-1854. doi: 10.1093/cid/ciz560. Apr 2020.